Dave Coulier Sets the Record Straight on Weight Loss and Voice While Battling Cancer

Dave Coulier popped back up on Instagram and, yeah, he knows you noticed he looks and sounds different. He explained why, and it is not a mystery diet: it is cancer treatment. The update is candid, a little tough, and ultimately encouraging.

Why he looks and sounds different right now

In a new video posted Thursday, May 7, the 66-year-old 'Full House' alum said the changes fans have clocked are fallout from radiation aimed at a carcinoma in his throat. He has not been able to eat solid food for months, dropped about 45 pounds during treatment, and the radiation has messed with his voice. None of that is shocking if you have been through or around head-and-neck radiation, but it does explain what you are seeing in his recent posts.

Two separate cancers, not connected

Here is the part that can get confusing, so let’s lay it out cleanly: Coulier has dealt with two different cancers in the last couple of years, and doctors consider them unrelated.

• November 2024: He announced a diagnosis of non-Hodgkin lymphoma.
• March 2025: After several rounds of chemo, he was told he was cancer-free from the lymphoma.
• December 2025: He learned he also had HPV-related oropharyngeal tongue cancer — a cancer in the throat/base of the tongue area that can be driven by the human papillomavirus. The CDC lists common symptoms like a lingering sore throat, ear pain, hoarseness, swollen lymph nodes, painful swallowing, and unplanned weight loss.
• February (on Good Morning America): He said he was in remission with both cancers and was going through a course of 35 radiation treatments.
• May 7 video: He updated fans on the radiation side effects, the weight loss, and why his voice has changed.

Where things stand now

Despite the rough side effects, Coulier shared some good news. His hair is starting to grow back after the 2025 chemo for lymphoma. Recent PET scans came in looking good for both the throat carcinoma and the lymphoma, and he says the prognosis is positive on both fronts. In other words: the plan is working.

"I am going to get on the other side of this. The silver lining here is that I had cancer, which helped me detect my other cancer."

That was Coulier back in December 2025, talking about the mental grind of back-to-back diagnoses. He has called the whole experience a roller coaster, but as of February he was in remission on both counts.

The support around him

His 'Full House' family has been loud about having his back. In December 2025, John Stamos, 62 at the time, called Coulier his hero and No. 1 inspiration, saying he had just seen him and that he was doing great — and, more importantly, showing people what it looks like to push through with kindness and resolve.

At home, Coulier has had steady support from his wife of 12 years, Melissa Bring. He is also dad to a grown son, Luc Coulier, from his first marriage to Jayne Modean, which lasted from 1990 to 1992.

Bottom line: Coulier knows he looks different right now. That is what radiation does. The bigger picture is the one that matters — he is in remission, scans look good, and he is still cracking updates with the same dry calm that made Joey Gladstone a thing in the first place.